• Danny M Takanishi, Elisabeth N Biuk-Aghai, Mihae Yu, Fedor Lurie, Hideko Yamauchi, Hao C Ho, Alyssa D Chapital, and Wega Koss.
• Department of Surgery, University of Hawaii, Honolulu, HI, USA. dtakanis@hawaii.edu
• Am. J. Surg. 2009 Feb 1;197(2):232-7.

BackgroundThis study evaluated whether commercially available blood volume measurements in critically ill surgical patients altered fluid management.MethodsPatients admitted to the surgical intensive care unit of a tertiary care teaching hospital were prospectively evaluated. The frequency of changes in fluid management when results of blood volume measurements were available was determined.ResultsIn a pilot study, the frequency of instances when measurement of blood volume would have altered fluid management was statistically significant (P = .0003). In 40 subsequent patients, treatment change occurred in 36% of instances when blood volume results were obtained (P < .001). In the majority, no immediate qualitative change in clinical status occurred, with a desirable clinical response in 39% and no negative treatment responses (P < .001).ConclusionsBlood volume measurements may assist in the management of critically ill surgical patients by providing a direct measure of intravascular volume. Further studies are warranted to determine its effect on outcome.

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