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Di Yi Jun Yi Da Xue Xue Bao · Nov 2002
Randomized Controlled Trial Clinical Trial[Inhibiting effect of intrathecal fentanyl on intraoperative vomiting during cesarean delivery under epidural anesthesia].
- Ming-Wen Ouyang, Miao-Ning Gu, and Chun-Shui Lin.
- Department of Anesthesia, Nanfang Hospital, First Military Medical University, Guangzhou 510515, China.
- Di Yi Jun Yi Da Xue Xue Bao. 2002 Nov 1;22(11):1037-8.
ObjectiveTo observe the inhibiting effect of intrathecal (IT) fentanyl on nausea and vomiting during cesarean delivery under epidural anesthesia.MethodsThirty healthy parturients (ASA grade I to II) were randomly assigned in equal numbers into control and fentanyl groups (n=15 each, patients in the latter group treated with IT fentanyl at the dose of 20 microgram/3ml). The incidence of nausea and vomiting during the elective cesarean delivery under epidural anesthesia between the 2 groups were compared and the neonates' Apgar scores assessed after the delivery.ResultsIntraoperative nausea and vomiting/retching were reduced in the IT fentanyl group as compared with the control group (6.7 % vs 33.3 % and 0 vs 26.7 %, P>0.05 and P<0.05 respectively). The neonates' Apgar scores were not significantly different between the 2 groups (P>0.05).ConclusionIT fentanyl can decrease intraoperative vomiting during cesarean delivery performed under epidural anesthesia.
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