• Internal medicine · Oct 2000

    Case Reports

    Catastrophic antiphospholipid antibody syndrome in systemic lupus erythematosus: an autopsy case report of a young woman.

    • R Mizuno, S Fujimoto, T Fujimoto, T Nishino, H Shiiki, T Hashimoto, S Nakamura, and K Dohi.
    • First Department of Internal Medicine, Nara Medical University.
    • Intern. Med. 2000 Oct 1;39(10):856-9.

    AbstractCatastrophic antiphospholipid syndrome (CAPS) is a severe variant of antiphospholipid syndrome (APS) characterized by disseminated microangiopathy that results in multiorgan failure. CAPS mainly occurs in association with systemic lupus erythematosus (SLE). Clinically, CAPS mimics disseminated SLE vasculitis, intravascular coagulation (DIC), and particularly thrombotic thrombocytopenic purpura (TTP). We describe an autopsy case of young woman with CAPS in SLE, which is difficult to differentiate from TTP secondary to SLE.

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