• Boiena Spila and Agnieszka Szumiłło.
• Katedra i Klinka Psychiatrii AM w Lublinie, Głuska.
• Psychiatr Pol. 2006 Nov 1;40(6):1061-8.

UnlabelledGabapentin is an anticonvulsant structurally similar to gamma - amino- butyric acid considered as the central acting GABA- analogue. It is used mostly as an antiepileptic agent. A constantly growing number of studies refer to its efficacy in the treatment of psychiatric disorders.AimTo audit the effectiveness of the gabapentin used as adjunctive treatment of intensified panic disorder.Material6 patients (5 women, 1 man, of mean age 44.2 years) treated with gabapentin in combined therapy of a mean dose 300 mg/d, lasting on average 196 days.MethodPatients were diagnosed using research criteria based on the ICD-10 and M.I.N.I.5.0.0.Results And ConclusionAdverse events were not observed and an addition of gabapentin into treatment brings improvement of the clinical condition. Complete amelioration was detected in 4 of the 6 patients. In one single year of observation panic disorder relapses were not observed even though there was a discontinuation of treatment. The presented case reports show a possibility of successful treatment with gabapentin in severe panic disorders.

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