• Obstetrics and gynecology · Oct 1995

    Case Reports

    Pregnancy in a combined liver and kidney transplant recipient with type 1 primary hyperoxaluria.

    • D G Skannal, L J Dungy-Poythress, M Miodovnik, and M R First.
    • Department of Obstetrics and Gynecology, University of Cincinnati College of Medicine, Ohio, USA.
    • Obstet Gynecol. 1995 Oct 1;86(4 Pt 2):641-3.

    BackgroundLittle is known about pregnancy outcomes in multiple organ transplant recipients. We present a case of pregnancy in a patient after liver and kidney transplantation for the genetic disorder of type 1 primary hyperoxaluria.CaseA 14-year-old Hispanic teenager presented with end-stage renal disease and had a kidney biopsy that revealed hyperoxaluria. A liver biopsy revealed type 1 primary hyperoxaluria. After a year of dialysis and worsening renal status, she underwent a combined orthotopic liver and kidney transplant. The patient subsequently became pregnant, but she required no antihypertensive therapy throughout the prenatal or postpartum period and showed no signs of renal or liver graft rejection. She delivered by cesarean at 38 weeks.ConclusionCombined liver and kidney transplant recipients who become pregnant can have a successful outcome.

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