• Neurosurg Focus · Jan 2006

    Review

    Intrathecal baclofen in the treatment of adult spasticity.

    • Joseph C Hsieh and Richard D Penn.
    • Section of Neurosurgery, University of Chicago, Illinois 60637, USA.
    • Neurosurg Focus. 2006 Jan 1;21(2):e5.

    AbstractMedical management of adult spasticity, a condition of increased muscle tone and deep tendon reflexes, is often challenging and complex. Oral medications such as baclofen often have unacceptable supraspinal side effects at effective doses. Intrathecal baclofen delivered by an implanted catheter and pump system provides good relief of spasticity while overcoming these limitations. In this paper the authors survey the use of oral and intrathecal baclofen therapy, detail the surgical process, and explain the risks and benefits of the procedure.

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