• J Neuropsychiatry Clin Neurosci · Jan 2010

    Relationship between cognitive status at admission and incident delirium in older medical inpatients.

    • José G Franco, Camila Valencia, Carolina Bernal, María V Ocampo, Paula T Trzepacz, Joan de Pablo, and Mario A Mejía.
    • Calle San Antonio, Numero 10, 1o 2a, Postal Code 43201, Reus, Spain. josefranco11@hotmail.com
    • J Neuropsychiatry Clin Neurosci. 2010 Jan 1;22(3):329-37.

    AbstractTo evaluate the relationship between cognitive status and incident delirium, 291 geriatric patients on internal medicine wards were evaluated on admission with the Mini-Mental State Examination (MMSE) and Confusion Assessment Method-Spanish. Those with incident delirium were assessed using the Delirium Rating Scale-Revised-98 (DRS-R98). Delirium incidence was 11.7%, and 82 patients (28.2%) had cognitive deficits on MMSE. As cognitive impairment worsened, the risk for delirium increased linearly, and for each unit of MMSE worsening the DRS-R98 severity score worsened 0.4 points (F=5.39, df=1, p=0.027). Optimal MMSE cutoff score from receiver-operating characteristic curve analysis was 24.5. Even mild cognitive deficits increase delirium risk and severity.

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