• Terrie Vasilopoulos, Timothy E Morey, Ketan Dhatariya, and Mark J Rice.
• From the Department of Anesthesiology, University of Florida College of Medicine, Gainesville, Florida; Elsie Bertram Diabetes Centre, Norfolk and Norwich University Hospitals, Norwich, United Kingdom; and... more Department of Anesthesiology, Vanderbilt University Medical Center, Nashville, Tennessee. less
• Anesth. Analg. 2016 Mar 1; 122 (3): 825-830.

AbstractModern clinical research commonly uses complex designs with multiple related outcomes, including repeated-measures designs. While multiple comparison corrections and effect size calculations are needed to more accurately assess an intervention's significance and impact, understanding the limitations of these methods in the case of dependency and correlation is important. In this review, we outline methods for multiple comparison corrections and effect size calculations and considerations in cases of correlation and summarize relevant simulation studies to illustrate these concepts.

10 keywords...

hide…