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The Journal of pediatrics · Sep 2000
Case ReportsAcute neurologic decompensation in an infant with cobalamin deficiency exposed to nitrous oxide.
- K Felmet, B Robins, D Tilford, and S J Hayflick.
- Departments of Pediatrics, Oregon Health Sciences University, Portland 97201, USA.
- J. Pediatr. 2000 Sep 1;137(3):427-8.
AbstractAfter exposure to nitrous oxide, an infant with unrecognized cobalamin deficiency developed neurologic deterioration and pancytopenia. Hematologic recovery and partial resolution of his neurologic changes followed repletion of the vitamin. Nitrous oxide depletes bioavailable cobalamin and may be a dangerous anesthetic in patients with cobalamin deficiency.
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