• Europace · Sep 2010

    Case Reports

    Should sevoflurane be used in the electrophysiology assessment of accessory pathways?

    • Jane C Caldwell, Clement Fong, and Sahrkaw A Muhyaldeen.
    • Manchester Heart Centre, Central Manchester and Manchester Children's University Hospital Trust, Manchester, UK. jane.caldwell@manchester.ac.uk
    • Europace. 2010 Sep 1;12(9):1332-5.

    AbstractSevoflurane has been shown to significantly prolong the action potential duration and the QTc interval. Despite this, clinical studies have shown only minor clinical effects on accessory pathway properties under general anaesthesia with sevoflurane compared with conscious sedation with midazolam. This case demonstrates significant prolongation of accessory pathway effective refractory period (APERP) under general anaesthetic with sevoflurane compared with propofol.

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