• Chest · Aug 2016

    Review

    Central airway obstruction: benign strictures, tracheobronchomalacia and malignancy-related.

    • Septimiu Dan Murgu, Katarine Egressy, Balaji Laxmanan, Guillermo Doblare, Rosamaria Ortiz-Comino, and D Kyle Hogarth.
    • Department of Medicine, Division of Pulmonary and Critical Care Medicine, University of Chicago, Chicago, IL. Electronic address: smurgu@medicine.bsd.uchiacgo.edu.
    • Chest. 2016 Aug 1; 150 (2): 426-41.

    AbstractThe purpose of this article is to provide an update on methods for palliating symptoms in patients with histologically benign and malignant central airway obstruction. We review the published literature within the past decade on postintubation, posttracheostomy, and TB- and transplant-related airway strictures; tracheobronchomalacia; and malignant airway obstruction. We review terminology, classification systems, and parameters that impact treatment decisions. The focus is on how airway stent insertion fits into the best algorithm of care. Several case series and cohort studies demonstrate that airway stents improve dyspnea, lung function, and quality of life in patients with airway obstruction. Airway stenting, however, is associated with high rates of adverse events and should be used only when curative open surgical interventions are not feasible or are contraindicated.Copyright © 2016 American College of Chest Physicians. Published by Elsevier Inc. All rights reserved.

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