• J Palliat Med · Apr 2016

    Neutrophil-Lymphocyte Ratio Predicts Survival in Terminal Cancer Patients.

    • Hee Kyung Ahn, In Cheol Hwang, Ji Sung Lee, Sun Jin Sym, Eun Kyung Cho, and Dong Bok Shin.
    • 1 Department of Internal Medicine, Gil Medical Center, Gachon University , Incheon, Republic of Korea.
    • J Palliat Med. 2016 Apr 1; 19 (4): 437-41.

    BackgroundNeutrophil-lymphocyte count ratio (NLR) is a prognostic factor in cancer, although its prognostic significance in terminally ill cancer patients is not clear.ObjectiveWe investigated the association of NLR with survival in patients with terminal cancer.MethodsWe retrospectively investigated 205 consecutive patients with terminal cancer admitted to a palliative care unit during 2014.ResultsThe median value of NLR was 9.7. In univariable analysis, NLR of 10 or more was significantly associated with shorter survival and NLR further discriminated survival of each palliative prognostic index (PPI) group. In multivariable analysis, increased NLR (≥10) was associated with shorter survival (hazards ratio [HR] 1.54, p<0.005), along with poor performance status (HR 1.55, p < 0.011), high PPI score (HR 1.59, p<0.003), and hyperbilirubinemia (HR 1.84, p < 0.001).ConclusionOur results suggest that elevated NLR was an independent prognostic factor for poor survival in patients with terminal cancer.

      Pubmed     Full text   Copy Citation     Plaintext  

      Add institutional full text...

    Notes

     
    Knowledge, pearl, summary or comment to share?
    300 characters remaining
    help        
    You can also include formatting, links, images and footnotes in your notes
    • Simple formatting can be added to notes, such as *italics*, _underline_ or **bold**.
    • Superscript can be denoted by <sup>text</sup> and subscript <sub>text</sub>.
    • Numbered or bulleted lists can be created using either numbered lines 1. 2. 3., hyphens - or asterisks *.
    • Links can be included with: [my link to pubmed](http://pubmed.com)
    • Images can be included with: ![alt text](https://bestmedicaljournal.com/study_graph.jpg "Image Title Text")
    • For footnotes use [^1](This is a footnote.) inline.
    • Or use an inline reference [^1] to refer to a longer footnote elseweher in the document [^1]: This is a long footnote..

    hide…