• Burns · Nov 2014

    Review Case Reports

    Pseudoangiosarcomatous squamous cell carcinoma developing on a burn scar: A case report and review of the literature.

    • Sung Hoon Koh, Suk Joon Oh, Huan Chun, and Seon Gyu Kim.
    • Department of Plastic and Reconstructive Surgery, Hallym University Sacred Heart Hospital, Anyangsi, Republic of Korea.
    • Burns. 2014 Nov 1;40(7):e47-52.

    AbstractPseudoangiosarcomatous squamous cell carcinoma, also known as pseudovascular, pseudovascular adenoid and pseudoangiomatous squamous cell carcinoma, is an exceedingly rare, aggressive variant of cutaneous squamous cell carcinoma with extreme acantholysis resulting in angiosarcoma-like areas. Histologically, a pseudoangiosarcomatous pattern includes complex anastomosing channels and spaces lined with neoplastic cells. The neoplastic cells exhibit cytokeratin and vimentin positivity but yield negative results with CD31 and CD34. This case report describes pseudoangiosarcomatous squamous cell carcinoma developing on a burn scar on the ankle. In this report, we emphasize the importance of establishing a diagnosis with histological and immunohistochemical examination, and we review the described incidence of the age and sites with the prognosis for the treatment of pseudoangiosarcomatous squamous cell carcinoma of the skin.Copyright © 2014 Elsevier Ltd and ISBI. All rights reserved.

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