• Int. J. Pediatr. Otorhinolaryngol. · Jul 2006

    Randomized Controlled Trial Comparative Study

    Ropivacaine compared to bupivacaine for post-tonsillectomy pain relief in children: a randomized controlled study.

    • Ertap Akoglu, B Cagla Ozbakis Akkurt, Kerem Inanoglu, Semsettin Okuyucu, and Safak Dagli.
    • Department of Otolaryngology, Mustafa Kemal University Medical Faculty, Araştirma Hastanesi, 31100 Antakya, Turkey.
    • Int. J. Pediatr. Otorhinolaryngol. 2006 Jul 1;70(7):1169-73.

    ObjectiveTo compare the effects of ropivacaine and bupivacaine on post-tonsillectomy pain in children.MethodsForty-six children aged 2-12 years, undergoing tonsillectomy were enrolled in the study. Group 1 (n=16) received bupivacaine, group 2 (n=15) received ropivacaine, and a group 3 (control) (n=15) received 9% NaCl (saline) infiltrated around each tonsil. Pain was evaluated using a modified Children's Hospital of Eastern Ontario Pain Scale (mCHEOPS) recorded 15 min and 1, 4, 12, 16, and 24h postoperatively.ResultsNo difference was found in the demographic data among the groups. The pain scores were similar between the bupivacaine and ropivacaine groups (p>0.05). The pain scores in both analgesia groups were significantly (p<0.05) lower 1, 4, 12, 16, and 24h postoperatively compared to the control group. Analgesic requirements and the time to first analgesia were also significantly (p<0.05) different between the analgesia and control groups.ConclusionLocal ropivacaine infiltration is a safe and effective method and equivalent to bupivacaine for post-tonsillectomy pain.

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