• Critical care clinics · Oct 2009

    Review

    Principles of source control in the management of sepsis.

    • John C Marshall and Abdullah al Naqbi.
    • Department of Surgery, Li Ka Shing Knowledge Institute, St Michael's Hospital, University of Toronto, Toronto, Ontario, Canada. marshallj@smh.toronto.on.ca
    • Crit Care Clin. 2009 Oct 1;25(4):753-68, viii-ix.

    AbstractThe term "source control" encompasses all those physical measures used to control a focus of invasive infection and to restore the optimal function of the affected area. Source-control measures can be categorized into 3 broad modalities: drainage controls the liquid component of an infection by converting a closed space infection to a controlled sinus or fistula; debridement is the physical removal of solid necrotic tissue (removal of an infected device can be considered a form of debridement); definitive measures seek to restore optimal function to the involved area. This article discusses specific approaches to source control in the abdomen, chest, and skin and soft tissues.

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