• Ann Card Anaesth · May 2011

    Case Reports

    Anesthetic management for combined mitral valve replacement and aortic valve repair in a patient with osteogenesis imperfecta.

    • Jiapeng Huang, Michelle Dinh, Nicholas Kuchle, and Jing Zhou.
    • Department of Anesthesia, Jewish Hospital and St. Mary's Healthcare, Louisville, KY, USA. jiapenghuang@yahoo.com
    • Ann Card Anaesth. 2011 May 1;14(2):115-8.

    AbstractOsteogenesis imperfecta is a rare disorder of connective tissues and presents multiple challenges, including difficult airway, hyperthermia, coagulopathy and respiratory dysfunction, for anesthesiologists, especially during cardiac surgery. We present anesthetic management of a patient with osteogenesis impertecta during double valve surgery. Dexmedetomidine infusion minimized the risks of malignant hyperthermia. Glidescope and in-line stabilization facilitated endotracheal intubation and protected his oral structures and cervical spine. Transesophageal echocardiography (TEE) diagnosed a flail A3 segment and redundant left coronary cusp causing mitral and aortic regurgitation. The mitral valve was replaced and the aortic valve repaired. Coagulopathy was corrected according to comprehensive coagulation analysis. Glidescope, dexmedetomidine, coagulation analysis and TEE could facilitate anesthetic management in these patients.

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