• Plast. Reconstr. Surg. · Jul 2005

    Randomized Controlled Trial

    Effects of mild hypothermia on blood coagulation in patients undergoing elective plastic surgery.

    • Maurizio Cavallini, Franz Wilhelm Baruffaldi Preis, and Andrea Casati.
    • Unit of Plastic Surgery, Galeazzi Hospital, Milan, Italy.
    • Plast. Reconstr. Surg. 2005 Jul 1;116(1):316-21; discussion 322-3.

    BackgroundThe aim of this prospective, controlled study was to evaluate the effects on coagulation function of active patient warming during elective plastic surgery.MethodsSeventy-six patients undergoing elective plastic surgery (additive and reductive mastoplasty, rhinoplasty, and liposuction) were either covered with standard sterile drapes (control group, n = 38) or actively warmed during surgery with countercurrent fluid warming and forced-air skin warming (treatment group, n = 38). Complete evaluation of the coagulation activity was performed 1 hour before general anesthesia was induced and then at the end of surgery.ResultsAlthough no differences in preoperative core temperature were observed (36.0 +/- 0.5 degrees C in the control group and 36.1 +/- 0.4 degrees C in the treatment group; p = 0.12), core temperature was lower at the end of surgery in the control group (34 +/- 1.0 degrees C) than in the treatment group (36 +/- 0.6 degrees C) (p = 0.0005). No differences in prothrombin time and fibrinogen plasma concentrations were observed between the two groups. At the end of surgery, control group patients showed significantly larger activated partial thromboplastin times (36.8 +/- 3.5 seconds) and bleeding times (8.1 +/- 1.6 minutes) as compared with patients maintained normothermic during surgery (34.0 +/- 2.9 seconds and 4.3 +/- 1.1 minutes; p = 0.0005 and p = 0.0005, respectively).ConclusionActively maintaining intraoperative normothermia allows patients to maintain normal coagulation function during elective plastic surgery lasting longer than 2 hours, potentially reducing the occurrence of bleeding-related complications after plastic surgery.

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