• Curr. Opin. Pediatr. · Apr 2011

    Review

    Accidental and iatrogenic causes of acute kidney injury.

    • Katherine Twombley, Michel Baum, and Jyothsna Gattineni.
    • Department of Pediatrics, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas 75390-9063, USA.
    • Curr. Opin. Pediatr. 2011 Apr 1;23(2):208-14.

    Purpose Of ReviewIngestions and iatrogenic administration of drugs are all too common causes of acute kidney injury. This review will discuss these preventable causes of acute kidney injury.Recent FindingsRecent studies have examined the pathophysiology of acute kidney injury by several commonly used drugs. These studies have shown that drugs and toxins can cause acute kidney injury by altering renal hemodynamics, direct tubular injury or causing renal tubular obstruction.SummaryKnowledge of the drugs that cause acute kidney injury and how this injury is manifested can lead to improved diagnosis and treatment with the ultimate goal of prevention.

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