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Randomized Controlled Trial Clinical Trial
Mouthpiece versus facemask for delivery of nebulized salbutamol in exacerbated childhood asthma.
- Masaru Kishida, Istuo Suzuki, Hirohiko Kabayama, Tatsuro Koshibu, Masako Izawa, Yukiko Takeshita, Fumiko Kurita, Mari Okada, Noriaki Shinomiya, and Tsugutoshi Aoki.
- Second Department of Pediatrics, Toho University School of Medicine, Tokyo, Japan. masa1114@polaris.med.toho-u.ac.jp
- J Asthma. 2002 Jun 1;39(4):337-9.
AbstractWe compared the bronchodilator response to salbutamol (albuterol) delivered by a compressed air nebulizer through a mouthpiece and via a facemask in 18 asthmatic children, to determine the most appropriate delivery method. Patients using a mouthpiece had significantly better mean percent increases in forced expiratory volume in 1 sec (FEV1) and in forced vital capacity (FVC) than those using a facemask 30 min after inhalation (FEV1, 56.4 +/- 32.6% vs. 28.9 +/- 19.1%, FVC: 34.4 +/- 26.4% vs. 7.5 +/- 14.9%, respectively). Nebulized therapy plays an important role in the management of bronchial asthma in children and should be delivered by a mouthpiece whenever possible in cases of exacerbated asthma.
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