• Carlos Blanco, Mayumi Okuda, John C Markowitz, Shang-Min Liu, Bridget F Grant, and Deborah S Hasin.
• Department of Psychiatry, College of Physicians and Surgeons New York State Psychiatric Institute, New York, New York, USA.
• J Clin Psychiatry. 2010 Dec 1;71(12):1645-56.

ObjectiveTo examine the prevalence of chronic major depressive disorder (CMDD) and dysthymic disorder, their sociodemographic correlates, patterns of 12-month and lifetime psychiatric comorbidity, lifetime risk factors, psychosocial functioning, and mental health service utilization.MethodFace-to-face interviews were conducted in the 2001-2002 National Epidemiologic Survey on Alcohol and Related Conditions (n = 43,093).ResultsThe 12-month and lifetime prevalences were greater for CMDD (1.5% and 3.1%, respectively) than for dysthymic disorder (0.5% and 0.9%, respectively). Individuals with CMDD and dysthymic disorder shared most sociodemographic correlates and lifetime risk factors for major depressive disorder. Individuals with CMDD and dysthymic disorder had almost identically high rates of Axis I and Axis II comorbid disorders. However, individuals with CMDD received higher rates of all treatment modalities than individuals with dysthymic disorder.ConclusionsIndividuals with CMDD and dysthymic disorder share many sociodemographic correlates, comorbidity patterns, risk factors, and course. Individuals with chronic depressive disorders, especially those with dysthymic disorder, continue to face substantial unmet treatment needs.© Copyright 2010 Physicians Postgraduate Press, Inc.

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