• Int. J. Clin. Pract. · Nov 2002

    Review

    Management of patients with intermittent claudication.

    • J W Olin.
    • Vascular Medicine Programme, Mount Sinai School of Medicine, The Zena and Michael A Wiener Cardiovascular Institute, New York, NY 10029-6574, USA.
    • Int. J. Clin. Pract. 2002 Nov 1;56(9):687-93.

    AbstractIntermittent claudication, the most common symptomatology of peripheral arterial disease, is characterised by lower-extremity discomfort induced by exercise and relieved by rest. The most serious potential outcome of the condition is increased morbidity and mortality from cardiovascular disease, with which it is often associated, thus prompt diagnosis and management are crucial. Therapy consists of structured exercise and reduction of cardiovascular risk factors, followed by or together with pharmacological interventions with anticlaudicants (cilostazol or pentoxifylline) and specific antiplatelet agents (aspirin, clopidogrel). Revascularisation procedures are indicated in those with limb-threatening or lifestyle disabling disease.

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