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Antimicrob. Agents Chemother. · Nov 2010
Clinical TrialTolerance of benznidazole in treatment of Chagas' disease in adults.
- María-Jesús Pinazo, José Muñoz, Elizabeth Posada, Paulo López-Chejade, Montserrat Gállego, Edgar Ayala, Elena del Cacho, Dolors Soy, and Joaquim Gascon.
- Tropical Diseases Section, Barcelona Centre for International Health Research, Hospital Clinic, Villarroel 170, Barcelona, Spain. mpinazo@clinic.ub.es
- Antimicrob. Agents Chemother. 2010 Nov 1;54(11):4896-9.
AbstractChagas' disease is an emerging public health problem in areas where the disease is not endemic. Treatment with benznidazole has shown efficacy in the acute stage of the disease, but its efficacy in the chronic stage remains controversial, and unwanted side effects are more frequent and severe in adults than in children. This study describes the profile of side effects of benznidazole in a cohort of Trypanosoma cruzi-infected patients in a European country.
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