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- Sheena Derry, Philip Wiffen, and Andrew Moore.
- Pain Research and Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, England.
- JAMA. 2016 Feb 23; 315 (8): 813-4.
Clinical QuestionAre topical nonsteroidal anti-inflammatory drugs (NSAIDs) associated with reduced pain intensity in acute musculoskeletal conditions, but without increased adverse events?Bottom LineWhen treating musculoskeletal conditions such as sprains, strains, and contusions, topical NSAIDs are associated with greater pain relief, but are not associated with an increase in adverse events compared with placebo.
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