• Ophthal Plast Reconstr Surg · Sep 2006

    Case Reports

    Thyroid eye disease presenting after cosmetic botulinum toxin injections.

    • Andrew R Harrison and Jonathan P Erickson.
    • Department of Ophthalmology, University of Minnesota Medical School, Minneapolis, Minnesota 55455, USA. aharrison@umn.edu
    • Ophthal Plast Reconstr Surg. 2006 Sep 1;22(5):397-8.

    AbstractA 53-year-old woman with left periorbital swelling 4 days after botulinum toxin injection in the lateral canthal area presented after noticing left eye prominence. Physical examination demonstrated proptosis and eyelid retraction. Computed tomography of the orbits confirmed extraocular muscle enlargement consistent with thyroid eye disease. In this case, the patient had development of proptosis after receiving botulinum toxin injections. Although the proptosis may represent progression of the patients' thyroid eye disease, it is worthwhile to consider incitation by botulinum toxin as a possible cause given its widespread use.

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