• Internal medicine · Jan 2013

    Review Case Reports

    Bacillus cereus necrotizing pneumonia in a patient with nephrotic syndrome.

    • Jun Miyata, Sadatomo Tasaka, Masaki Miyazaki, Syuichi Yoshida, Katsuhiko Naoki, Koichi Sayama, Koichiro Asano, Hiroshi Fujiwara, Kiyofumi Ohkusu, Naoki Hasegawa, and Tomoko Betsuyaku.
    • Division of Pulmonary Medicine, Department of Medicine, Keio University School of Medicine, Japan.
    • Intern. Med. 2013 Jan 1;52(1):101-4.

    AbstractBacillus cereus (B. cereus) is a Gram-positive rod that is widely distributed in the environment and can be a cause of food poisoning. We herein present a case of B. cereus necrotizing pneumonia in a patient with nephrotic syndrome under corticosteroid treatment after developing transient gastroenteritis symptoms. B. cereus was isolated from bronchial lavage fluid and transbronchial biopsy specimens. A multiplex polymerase chain reaction analysis of the toxin genes revealed a strain possessing enterotoxicity. The patient recovered after one week of intravenous meropenem followed by a combination of oral moxifloxacin and clindamycin. B. cereus is a pathogen that causes necrotizing pneumonia in immunocompromised hosts.

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