• Jochen P Windfuhr, Yue-Shih Chen, Evan J Propst, and Christian Güldner.
• Department of Otorhinolaryngology, Plastic Head and Neck Surgery, Kliniken Maria Hilf Mönchengladbach, 41061 Mönchengladbach, Germany. hfdoliveira@yahoo.com.br
• Braz J Otorhinolaryngol. 2011 Jun 1;77(3):373-9.

UnlabelledIt has been stated, that the administration of Dexamethasone has an impact on the morbidity following tonsillectomy.ObjectiveTo re-calculate the blood values for Dexamethasone when given as fixed doses and to evaluate the effect of Dexamethasone on post-operative nausea, vomiting and bleeding rates following tonsillectomy.Materials And MethodsThe charts of 272 children (2-15 years) who had undergone tonsillectomy were analyzed. The rates of post-operative nausea, vomiting and bleeding in relation to Dexamethasone were calculated-in general and different doses (0 mg/kg, <0.15 mg/kg, >0.15 mg/kg).Study DesignRetrospective cohort study.ResultsDexamethasone was administered in 121 children (43.7%) according to the preference of the anesthesist (mean dose: 0.2 +/- 0.12 mg/kg; range: 0.04 - 0.62 mg/kg). There was no significant difference in nausea and vomiting (p=0.953) or bleeding (p=0.827) across groups receiving or not receiving Dexamethasone. Stratification into three different groups of Dexamethasone concentration also did not identify a dose-related risk of postoperative nausea or vomiting (p=0.98) or bleeding (p=0.71).ConclusionAt least under common non-controlled conditions in the clinic, Dexamethasone does not appear to have an effect on nausea or vomiting or bleeding following tonsillectomy.

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