• Semin. Pediatr. Surg. · Nov 1996

    Review

    Innovative therapies in the management of newborns with congenital diaphragmatic hernia.

    • R B Hirschl.
    • Department of Surgery, CS Mott Children's Hospital, University of Michigan, Ann Arbor 48109-0245, USA.
    • Semin. Pediatr. Surg. 1996 Nov 1;5(4):256-65.

    AbstractA number of innovative approaches have been explored in the hope of improving the outcome in newborns with congenital diaphragmatic hernia (CDH) and respiratory insufficiency. Among these are the techniques of delayed approach to the repair of the diaphragmatic hernia; permissive hypercapnia; nitric oxide and surfactant administration; intratracheal pulmonary ventilation; liquid ventilation; perfluorocarbon-induced lung growth; and lung transplantation. Although early in their clinical evolution, these interventions are developing rapidly and hold promise for improving the outcome in patients with CDH.

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