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Review Case Reports
Intraventricular tissue plasminogen activator for intraventricular hemorrhage caused by an arteriovenous malformation.
- Kelley Keefe, Meysam Kebriaei, Andrew Gard, and Arun-Angelo Patil.
- Division of Neurosurgery, Department of Surgery, 982035 University of Nebraska Medical Center, Omaha, NE 68198-2035, USA. Electronic address: kmkeefe@unmc.edu.
- J Clin Neurosci. 2014 Mar 1;21(3):526-9.
AbstractThe use of thrombolytics delivered through an external ventricular drain has improved outcomes in intraventricular hemorrhage, a disease with a poor prognosis; however, presence of an arteriovenous malformation is generally considered a contraindication to thrombolytic use. Due do the high mortality with the current standard of care, thrombolytics should be considered as an acceptable treatment option despite the presence of an arteriovenous malformation in certain clinical situations. We review the available literature and present an additional patient to make the case for the use of thrombolytics for intraventricular hemorrhage from an arteriovenous malformation.Copyright © 2013 Elsevier Ltd. All rights reserved.
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