• Neurol. Med. Chir. (Tokyo) · Jan 2010

    Case Reports

    Mild encephalitis/encephalopathy with a reversible splenial lesion: evaluation by diffusion tensor imaging. Two case reports.

    • Satoru Osuka, Hironori Imai, Eiichi Ishikawa, Akira Matsushita, Tetsuya Yamamoto, Hiroki Nozue, Tatsuyuki Ohto, Kousaku Saotome, Yoji Komatsu, and Akira Matsumura.
    • Department of Neurosurgery, Institute of Clinical Medicine, Graduate School of Comprehensive Human Sciences, University of Tsukuba, Ibaraki.
    • Neurol. Med. Chir. (Tokyo). 2010 Jan 1;50(12):1118-22.

    AbstractMild encephalitis/encephalopathy with a reversible splenial lesion (MERS) is a clinico-radiological syndrome with a very particular clinical course. Three patients with MERS were evaluated by various sequences of magnetic resonance imaging with diffusion tensor imaging. Initial diffusion-weighted imaging showed reduction in the apparent diffusion coefficient values in the lesions, which completely resolved with the elimination of symptoms. However, diffusion anisotropy of the lesions showed no remarkable abnormalities in the early or delayed phases. These results may indicate that white matter architecture is preserved in both early and delayed phases in MERS.

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