• Blood Coagul. Fibrinolysis · Sep 2009

    Review Case Reports

    Unusual presentation of Lemierre's syndrome: two cases and a review.

    • Matthijs van Wissen, Victor E A Gerdes, Eric C M van Gorp, Dees P M Brandjes, and Marcel Soesan.
    • Department of Internal Medicine, Slotervaart Hospital, Amsterdam, The Netherlands. Matthijs.vanWissen@slz.nl
    • Blood Coagul. Fibrinolysis. 2009 Sep 1;20(6):466-9.

    AbstractLemierre's syndrome is a potentially fatal disease that usually presents with oropharyngeal infection, followed by sepsis, thrombosis of the internal jugular vein and septic emboli. Most cases are caused by the Gram-negative, anaerobic Fusobacterium necrophorum. We present two patients with an atypical presentation of Lemierre's syndrome and a review. These cases illustrate that a positive blood culture for F. necrophorum, even without the presence of clinical symptoms pointing towards thrombosis of the internal jugular vein, justifies further radiological testing for thrombophlebitis of the internal jugular vein.

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