• Arthritis and rheumatism · May 1993

    Pressure pain threshold in pain-free subjects, in patients with chronic regional pain syndromes, and in patients with fibromyalgia syndrome.

    • G Granges and G Littlejohn.
    • Rheumatology Unit, Monash Medical Centre, Melbourne, Australia.
    • Arthritis Rheum. 1993 May 1;36(5):642-6.

    ObjectiveWe hypothesized that change in pain threshold to pressure reflects a generalized change in the pain system affecting both tender and control points.MethodsWe assessed 18 tender points and 4 control points using an algometer in 60 patients with generalized fibromyalgia/fibrositis syndrome, 60 patients with localized chronic pain syndromes, and in 60 pain-free subjects.ResultsA significant correlation was found between myalgia scores at tender points and control points in these subjects.ConclusionThese results suggest that there is a diffuse change in pain modulation in fibromyalgia, as hypothesized, but the tender point is still clinically useful.

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