• J. Trop. Pediatr. · Jun 2010

    Randomized Controlled Trial Comparative Study

    A pilot study of comparison of BCPAP vs. VCPAP in preterm infants with early onset respiratory distress.

    • Amit Tagare, Sandeep Kadam, Umesh Vaidya, Anand Pandit, and Sanjay Patole.
    • Division of Neonatology, Department of Pediatrics, KEM Hospital, Rasta Peth, Pune 411011, India.
    • J. Trop. Pediatr. 2010 Jun 1;56(3):191-4.

    BackgroundBubble continuous positive airway pressure (BCPAP) is a low-cost nasal CPAP delivery system with potential benefits for developing nations. The objective of the study was to compare the efficacy and safety of BCPAP with ventilator CPAP (VCPAP) in preterm neonates with moderate respiratory distress.MethodsIn a pilot randomized controlled trial, 30 preterm neonates (gestation <37 weeks) with Silverman-Anderson score between 5 to 7 and oxygen requirement >30% within first 6 h of life were randomly allocated to BCPAP or VCPAP after informed parental consent. Proportion of neonates with success or failure, while using the allocated mode of CPAP delivery (primary outcome) was compared.ResultsThe success rate was comparable [VCPAP: 80% (12/15) vs. BCPAP: 87% (13/15)] between the two groups. Dislodgement was commonest problem with equal frequency [10/15, (67%)] in each group.ConclusionBCPAP appears to be a promising method of CPAP delivery in preterm neonates with moderate respiratory distress.

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