• J Med Case Rep · Jan 2014

    Review Case Reports

    Aeromonas sobria necrotizing fasciitis and sepsis in an immunocompromised patient: a case report and review of the literature.

    • Savino Spadaro, Angela Berselli, Elisabetta Marangoni, Anna Romanello, Maria Vittoria Colamussi, Riccardo Ragazzi, Silvia Zardi, and Carlo Alberto Volta.
    • Department of Morphology, Surgery and Experimental Medicine, Sant' Anna Hospital, University of Ferrara, Via Aldo Moro 8, Ferrara, FE 44124, Italy. savinospadaro@gmail.com.
    • J Med Case Rep. 2014 Jan 1;8:315.

    IntroductionAeromonas veronii biovar sobria is a rare cause of bacteremia, with several studies indicating that this isolate may be of particular clinical significance since it is enterotoxin producing. A wide spectrum of infections has been associated with Aeromonas species in developing countries that include gastroenteritis, wound infections, septicemia and lung infections. This infection, caused by Aeromonas species, is usually more severe in immunocompromised than immunocompetent individuals. We here describe a case of soft tissue infection and severe sepsis due to Aeromonas sobria in an immunocompromised patient.Case PresentationA 74-year-old Caucasian man with a clinical history of chronic lymphocytic leukemia and immune thrombocytopenia, periodically treated with steroids, was admitted to our Intensive Care Unit because of necrotizing fasciitis and multiorgan failure due to Aeromonas sobria, which resulted in his death. The unfortunate coexistence of a Candida albicans infection played a key role in the clinical course.ConclusionOur experience suggests that early recognition and aggressive medical and surgical therapy are determinants in the treatment of severe septicemia caused by an Aeromonas sobria in an immunocompromised patient.

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