• Urology journal · Jan 2013

    Randomized Controlled Trial Comparative Study

    Unwanted intra-operative penile erection during pediatric hypospadiasis repair. Comparison of propofol and halothane.

    • Hamid Reza Abbasi, Seyed Soheil Ben Razavi, Mohammad Reza Hajiesmaeili, Shekoufeh Behdad, Mohammad Mehdi Ghiamat, and Ahmad Eghbali.
    • Department of Anesthesiology and Critical Care Medicine, Parsian Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran. mr-hajiesmaeili@razi.tums.ac.ir.
    • Urol J. 2013 Jan 1;10(3):988-92.

    PurposeTo compare the erectile effect of propofol and halothane on unwanted intraoperative penile erection (UIOPE) during pediatric hypospadiasis repair.Materials And MethodsOne hundred and seventeen boys who were in the age range of 6 months to 6 years and referred for hypospadiasis repair to our referral teaching hospital were included in this randomized clinical trial. Patients were randomly assigned to one of the two study groups before anesthesia induction. Anesthesia was maintained with a continuous intravenous infusion of propofol and inhalational halothane in the propofol (P) and halothane (H) groups, respectively. Data regarding the patients’ age, weight, pre- and intra-operative chordee, UIOPE, anesthesia time, surgery time, hematoma formation, and wound infection were collected. The Chi-Square and Fisher’s exact tests were used for comparison.ResultsNo statistically significant differences were noted regarding age, weight, and pre and intra-operative chordee between the two groups. The incidence of UIOPE (10.34% versus 57.63%; P = .000), anesthesia time (174.15 +/- 15.02 versus 181.26 +/- 15.19; P =.012), and surgery time (162.34 +/- 12.99 versus 167.69 +/- 13.90 +/- 13.90; P = .034) were significantly lower in group P compared with group H.ConclusionThe use of propofol during hypospadiasis surgical repair is more safe and effective than halothane in preventing UIOPE and reducing surgery and anesthesia time.

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