• Liang Shen, Yan Luo, Zhijun Lu, Xiang Hu, Wen Ding, and Buwei Yu.
• Department of Anesthesiology, Ruijin Hospital Luwan Branch, Shanghai Jiaotong University School of Medicine Shanghai 200020, China.
• Int J Clin Exp Med. 2014 Jan 1;7(12):5744-50.

ObjectivesTo compare the cost-effectiveness of inhalation of sevoflurane, target-controlled infusion (TCI) of propofol, intravenous (IV) propofol for induction-inhalation of sevoflurane, and IV propofol for induction-inhalation of desoflurane for anesthesia maintenance in day surgery.Methods240 patients, scheduled for elective day surgery, were randomly divided into 4 groups (n = 60 each): inhalation of sevoflurane anesthesia group (group S); TCI of propofol anesthesia (group P); and intravenous propofol for induction of anesthesia-inhalation of sevoflurane for maintenance of anesthesia group (group PS); and intravenous propofol for induction of anesthesia-inhalation of desoflurane for maintenance of anesthesia group (group PD).ResultsGroup S was associated with less time to loss of consciousness, as well as the other three groups were associated with less time to recovery (P < 0.05). Group P was associated with a higher anesthetic agents cost than other 3 groups (P < 0.05), and group S was associated with a higher anesthetic agents costs than group PS and PD (P < 0.05).ConclusionInduction with intravenous injection of propofol and maintenance with inhalation of desoflurane is the most cost-effective method of anesthesia for day surgery.

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