• Clin. Infect. Dis. · Nov 2013

    Higher incidence of acute kidney injury with intravenous colistimethate sodium compared with polymyxin B in critically ill patients at a tertiary care medical center.

    • Darowan S Akajagbor, Sharon L Wilson, Kapana D Shere-Wolfe, Paul Dakum, Manhattan E Charurat, and Bruce L Gilliam.
    • Department of Pharmacy Practice, D'Youville College School of Pharmacy, Buffalo.
    • Clin. Infect. Dis. 2013 Nov 1;57(9):1300-3.

    AbstractNephrotoxicity was assessed in 173 critically ill patients receiving intravenous colistin or polymyxin B; it occurred in 60.4% and 41.8%, respectively. Further investigation is necessary to elucidate the reason for the difference in nephrotoxicity observed between the groups and to assess the impact of severity of illness and dosing/administration.

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