• Rev Bras Ter Intensiva · Oct 2013

    Comparative Study Observational Study

    A comparison of gradual sedation levels using the Comfort-B scale and bispectral index in children on mechanical ventilation in the pediatric intensive care unit.

    • Cláudia da Costa Silva, Marta Maria Osório Alves, Michel Georges dos Santos El Halal, Sabrina dos Santos Pinheiro, and Paulo Roberto Antonacci Carvalho.
    • Hospital das Clínicas de Porto Alegre, Unidade de Terapia Intensiva Pediátrica, Porto AlegreRS, Brasil, Unidade de Terapia Intensiva Pediátrica, Hospital das Clínicas de Porto Alegre - HCPA - Porto Alegre (RS), Brasil.
    • Rev Bras Ter Intensiva. 2013 Oct 1;25(4):306-11.

    ObjectiveCompare the scores resulting from the Comfort-B scale with the bispectral index in children in an intensive care unit.MethodsEleven children between the ages of 1 month and 16 years requiring mechanical ventilation and sedation were simultaneously classified based on the bispectral index and the Comfort-B scale. Their behavior was recorded using digital photography, and the record was later evaluated by three independent evaluators. Agreement tests (Bland-Altman and Kappa) were then performed. The correlation between the two methods (Pearson correlation) was tested.ResultsIn total, 35 observations were performed on 11 patients. Based on the Kappa coefficient, the agreement among evaluators ranged from 0.56 to 0.75 (p<0.001). There was a positive and consistent association between the bispectral index and the Comfort-B scale [r=0.424 (p=0.011) to r=0.498 (p=0.002)].ConclusionDue to the strong correlation between the independent evaluators and the consistent correlation between the two methods, the results suggest that the Comfort-B scale is reproducible and useful in classifying the level of sedation in children requiring mechanical ventilation.

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