• Eur J Radiol · May 2012

    Review Meta Analysis

    The role of arterial embolization in controlling pelvic fracture haemorrhage: a systematic review of the literature.

    • Costas Papakostidis, Nikolaos Kanakaris, Rozalia Dimitriou, and Peter V Giannoudis.
    • Department of Trauma and Orthopaedics"G. Hatzikostas" General Hospital, Makriyianni Avenue, 45001 Ioannina, Greece. epappa@ioa.forthnet.gr
    • Eur J Radiol. 2012 May 1;81(5):897-904.

    ObjectiveTo evaluate the efficacy of emergency transcatheter arterial embolization (TAE) in controlling retroperitoneal arterial haemorrhage associated with unstable pelvic fractures.MethodsA systematic review of the English literature yielded 21 eligible studies published from 1979 to 2010. Evaluation of clinical and methodological heterogeneity was based on recording certain descriptive characteristics in the component studies. Statistical heterogeneity was detected using Cochran chi-square and I square tests and, when absent, a pooled estimate of effect size for each outcome of interest was calculated. The principal outcomes of interest were efficacy rate of TAE to control intrapelvic bleeding, mortality rates and frequency of associated complications.ResultsAll component studies were assigned a low to moderate quality score. Methodological and clinical heterogeneity was evident across component studies, but not strongly associated with the observed results. The efficacy rate of TAE ranged from 81 to 100%, while the frequency of repeat TAE for effective control of haemorrhage was 10% (95% CI: 7-13%, range: 0-19%). TAE was associated with an overall mortality ranging from 7 to 47%, and a 0-25% mortality due to intrapelvic bleeding (pooled estimate of effect size: 6%, 95% CI: 4-8%). A very low rate of associated complications were recorded in the component studies (pooled estimate of effect size: 1.1%, 95% CI: 0.1-2.1%).ConclusionTAE is an efficient acute intervention for controlling severe arterial bleeding related to pelvic trauma with a low complication rate. Repeat of the procedure is occasionally necessary before the effective haemorrhage control.Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.

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