• Benoît Vivien, Nicolas Deye, Bruno Mégarbane, Jean-Sébastien Marx, Pascal Leprince, Nicolas Bonnet, France Roussin, Laurent Jacob, Alain Pavie, Frédéric J Baud, and Pierre Carli.
• Département d'Anesthésie-Réanimation, Hôpital Necker Enfants Malades, Paris, France. benoit.vivien@nck.aphp.fr
• Ann Emerg Med. 2010 Oct 1;56(4):409-12.

AbstractUse of cardiac allograft for transplantation from donors after acute poisoning is a matter of debate because of potential toxic organ injuries, especially if death results from massive ingestion of cardiotoxic drugs. We report successful allograft cardiac transplantation from a brain-dead patient after severe flecainide and betaxolol self-poisoning requiring extracorporeal life support. Extracorporeal life support was initiated in the emergency department because of a refractory cardiac arrest caused by the cardiotoxicants' ingestion and continued after the onset of brain death to facilitate organ donation of the heart, liver, and kidneys. Forty-five months later, each organ recipient was alive, with normal graft function.Copyright © 2010 American College of Emergency Physicians. Published by Mosby, Inc. All rights reserved.

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