• Neurology · Nov 2006

    Acute hypothalamic stimulation and ongoing cluster headache attacks.

    • M Leone, A Franzini, G Broggi, E Mea, A Proietti Cecchini, and G Bussone.
    • Department of Neurology and Headache Centre, Istituto Nazionale Neurologico Carlo Besta, via Celoria 11, 20133 Milano, Italy. leone@istituto-besta.it
    • Neurology. 2006 Nov 28;67(10):1844-5.

    AbstractLong-term hypothalamic stimulation is effective in improving drug-resistant chronic cluster headache (CH). We assessed acute hypothalamic stimulation to resolve ongoing CH attacks in 16 patients implanted to prevent chronic CH, investigating 136 attacks. A pain intensity reduction of > or =50% occurred in 25 of 108 evaluable attacks (23.1%). Acute hypothalamic stimulation is not effective in resolving ongoing CH attacks, suggesting that hypothalamic stimulation acts by complex mechanisms in CH prevention.

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