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- Kannan Ramar and Catherine S H Sassoon.
- Pulmonary and Critical Care Section, Department of Medicine, University of California, Irvine, Medical Center, Orange, CA 92868, USA.
- Respir Care Clin N Am. 2005 Jun 1;11(2):307-17.
AbstractDuring conventional mechanical ventilation, fixed set pressure, flow, and tidal volume result in a mismatch between patient and ventilator inspiratory time and in a patient's inability to adapt to changing ventilatory demand. Synchrony between the patient and ventilator improves neuromuscular coupling and the ability to adapt to increased ventilatory demand or loading. The sensation of dyspnea prevents ineffective inspiratory efforts and attenuates periodic breathing during sleep.
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