• Expert Opin Pharmacother · May 2015

    Review

    Postoperative nausea and vomiting - a narrative review of pathophysiology, pharmacotherapy and clinical management strategies.

    • Thomas Wiesmann, Peter Kranke, and Leopold Eberhart.
    • University Hospital Giessen and Marburg, Campus Marburg, Philipps University Marburg, Department of Anesthesiology and Intensive Care Medicine , Baldingerstrasse, 35037 Marburg , Germany.
    • Expert Opin Pharmacother. 2015 May 1;16(7):1069-77.

    IntroductionPostoperative nausea and vomiting (PONV) are common complications concerning patients undergoing general anesthesia. Intensive research was performed during the last two decades in order to develop therapeutic and prophylactic strategies to prevent this complication.Areas CoveredThis article reviews the pathophysiology as well as pharmacological aspects of PONV prophylaxis and treatment. Relevant strategic aspects for pharmacological prophylaxis of PONV are discussed and clinical standard operating procedures are presented.Expert OpinionThe expert opinion focuses on poor implementation of actual PONV guidelines and future considerations.

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