• Lukas M Wildi, Michael O Kurrer, Arnaldo Benini, Dominik Weishaupt, Beat A Michel, and Pius Brühlmann.
• Department of Rheumatology, University Hospital, Zürich, Switzerland.
• J Spinal Disord Tech. 2004 Oct 1;17(5):395-400.

ObjectiveThe objective of this work was to investigate the clinical and histologic features of patients with pseudocystic lesions of the ligamentum flavum in the lumbar region of the spinal canal and ascertain the existence of genuine ligamentum flavum pseudocysts.MethodsRetrospective chart and histologic study of a patient cohort with lumbar radiculopathy due to a cystic intraspinal lesion and who had undergone decompressive surgery was conducted. Intraoperatively, the stenosing process had been found to be different from common etiologic entities and had been submitted for histologic examination.ResultsThe 33 patients with symptoms and signs of lumbar radiculopathy were between 48 and 85 years of age (mean 63.5 years). Twenty (61%) of them were women. All patients showed degenerative changes of the bony structures of the spine by conventional radiography. Segmental instability due to degeneration of the lumbar spine was present in 45%. Computed tomography and/or magnetic resonance imaging showed a cystic lesion. Clinical and histologic examination confirmed their origin from within the severely degenerated ligamentum flavum.ConclusionsRadiologic, surgical, and histologic findings suggest that the pseudocystic degeneration of the ligamentum flavum represents a genuine entity that is associated with degenerative changes of the structures of the respective lumbar spine segment. These pseudocystic lesions may compress the adjacent nerve roots, provoking symptoms and signs of radiculopathy. The findings suggest that the surgical treatment not only must consist of removal of the pseudocyst but must also include a radical extirpation of the ligamentum flavum surrounding the pseudocyst to avoid recurrence of such a lesion.

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