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Case Reports
Extracorporeal membrane oxygenation for the treatment of adult sickle cell acute chest syndrome.
- Ken Parhar, Barbora Parizkova, Nicola Jones, Kamen Valchanov, Jo-Anne Fowles, Martin Besser, Paul Telfer, Banu Kaya, Alain Vuylsteke, and Antonio Rubino.
- Department of Anaesthesia and Intensive Care, Papworth Hospital, Cambridge, UK ken.parhar@albertahealthservices.ca.
- Perfusion. 2016 Apr 1; 31 (3): 262-5.
AbstractSickle cell disease (SCD) is a hereditary haemoglobinopathy that results in polymerization of haemoglobin molecules and subsequent vaso-occlusion. A common cause of death in adults is acute chest syndrome (AChS) with resulting hypoxemic respiratory failure.Veno-venous extracorporeal membrane oxygenation (VV-ECMO) has been used successfully in acutely reversible respiratory failure when conventional mechanical ventilation has been unable to adequately oxygenate and ventilate in a lung-protective fashion.We present an adult SCD patient with severe respiratory failure due to AChS, successfully treated with VV-ECMO. We also discuss some of the technical challenges and considerations when using ECMO in the SCD patient.© The Author(s) 2015.
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