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- Yen-Michael S Hsu and George J Despotis.
- From the Department of Pathology and Immunology, Washington University in St. Louis School of Medicine, St. Louis, Missouri.
- A A Case Rep. 2014 Apr 15;2(8):92-4.
AbstractIn this report, we review 2 cases of coronary revascularization in patients with a diagnosis of coronary artery disease and preoperative protein S deficiency, an established hypercoagulable condition. In an attempt to normalize protein S levels, fresh frozen plasma was used as the priming fluid for the cardiopulmonary bypass circuit before the initiation of extracorporeal circulation. On the basis of a low risk of bleeding and the theoretical risk of thrombosis, neither patient received intraoperative antifibrinolytic treatment nor did they develop perioperative thrombotic complications.
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