• J Clin Monit Comput · Apr 2015

    Review

    Automation of anaesthesia: a review on multivariable control.

    • Jing Jing Chang, S Syafiie, Raja Kamil, and Thiam Aun Lim.
    • Department of Chemical and Environmental Engineering, Faculty of Engineering, Universiti Putra Malaysia, 43400 , Serdang, Selangor, Malaysia.
    • J Clin Monit Comput. 2015 Apr 1; 29 (2): 231-9.

    AbstractAnaesthesia is a multivariable problem where a combination of drugs are used to induce desired hypnotic, analgesia and immobility states. The automation of anaesthesia may improve the safety and cost-effectiveness of anaesthesia. However, the realization of a safe and reliable multivariable closed-loop control of anaesthesia is yet to be achieved due to a manifold of challenges. In this paper, several significant challenges in automation of anaesthesia are discussed, namely model uncertainty, controlled variables, closed-loop application and dependability. The increasingly reliable measurement device, robust and adaptive controller, and better fault tolerance strategy are paving the way for automation of anaesthesia.

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