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- Sonia Vaida, Hamid Al-Mondhiry, Dmitri Bezinover, Lauren Welsh, Serdar Ural, and Piotr Janicki.
- From the Department of Anaesthesiology, Penn State Milton S. Hershey Medical Center, Hershey, Pennsylvania.
- A A Case Rep. 2013 Dec 15; 1 (6): 86-8.
AbstractInherited Factor V deficiency is a rare bleeding disorder. We describe the genetic analysis and anesthetic management of a parturient with severe Factor V deficiency who presented in spontaneous labor. Good hemostatic conditions were obtained with prophylactic fresh frozen plasma administration of 10 mL/kg. Detailed genetic analysis by next-generation sequencing identified several relevant mutations in the coding part of the Factor V (F5) gene in our patient, her parents, and the newborn.
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