• Practical neurology · Jun 2011

    Case Reports

    The opsoclonus–myoclonus syndrome.

    • Jitendra Kumar Sahu and Kameshwar Prasad.
    • Department of Neurology, All India Institute of Medical Sciences, New Delhi, India.
    • Pract Neurol. 2011 Jun 1;11(3):160-6.

    AbstractThe opsoclonus–myoclonus syndrome is a rare and distinct neurological disorder characterised by rapid multidirectional conjugate eye movements (opsoclonus), myoclonus and ataxia, along with behavioural changes in adults and irritability in children. Sometimes it is due to a self-limiting presumed para-infectious brainstem encephalitis but it may also represent a non-metastatic manifestation of neuroblastoma in children and small cell carcinoma of the lung in adults. In this article, we will describe the clinical features, diagnosis, pathogenesis and management.

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