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Antimicrob. Agents Chemother. · Sep 1996
Case ReportsOnce-daily aminoglycoside therapy: potential ototoxicity.
- C Singer, C Smith, and D Krieff.
- Department of Medicine, Long Island Jewish Medical Center, Albert Einstein College of Medicine, New Hyde Park, New York 11040, USA.
- Antimicrob. Agents Chemother. 1996 Sep 1;40(9):2209-11.
AbstractCurrent data indicate that once-daily aminoglycoside therapy is as efficacious as traditional multiple daily dosing and equally or less toxic. Our experience with once-daily gentamicin, 6 mg/kg of body weight led to a 10% (3 of 33 patients) occurrence of documented ototoxicity after prolonged aminoglycoside exposure.
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