• Kiyoko Bito, Satoshi Higuchi, Azusa Omura, Yuri Kaneda, Reiko Otaki, Satomi Azuma, Mikiko Kojima, Naoki Otsuka, Kenji Shida, and Kazumasa Yasumoto.
• Masui. 2015 Mar 1;64(3):294-300.

BackgroundThis study was designed to evaluate the effects of perioperative administration of an isotonic electrolyte solution with 1% glucose (IT) on blood sodium (Na+) and blood glucose (BG) concentrations in pediatric patients < 1-year-old undergoing plastic surgery in comparison with a conventional hypotonic electrolyte solution with 2.6% glucose (HT).MethodsFifty Patients were randomly allocated to HT group and IT group. Na+ and BG were measured at induction of anesthesia (Tind), the end of surgery (Tend), and 4 hours after surgery (T4h).ResultsPatient characteristics were similar for the 2 groups. In the HT group, Na+ at Tend insignificantly dropped compared with that at Tind, whereas in the IT group Na+ was significantly elevated. Na+ at T4h significantly increased compared with that at Tend in each group. No cases developed new dysnatremia or dysglycemia in IT group. The incidence of hyponatremia at Tend was significantly lower in the IT group. A positive correlation between intraoperative Na+ concentration changes and the infusion duration was observed in the IT group.ConclusionsIsotonic solution with 1% glucose is suggested to be safe in infants during and after surgery.

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